OVERVIEW OF THE RESEARCH PROGRAMME
Innovation in tendon medicine is a promising frontier to respond to the urgent societal/economic healthcare demand determined by the worldwide growing incidence of tendinopathy. Perspectives For Future Innovation in Tendon repair (P4 FIT) fosters to build a new generation of 15 early stage researchers (ESRs) with adequate skills to explore non-conventional therapeutic and diagnostic solutions by exploiting the technological advances in nanomedicine.
The University of Helsinki brings together world-renowned academic and non-academic EU institutions, covering most of the basic and technological disciplines of the fields to launch a unique EJD. The inter-disciplinary, inter-sectoral, and international high quality educational environment will booster innovation-driving training and research leadership grounded in excellence for widening success in P4 medicine (predictive, preventive, personalized and participatory), promoting tendinopathy resolution.
P4 FIT will encourage cross-disciplinary working under the coordination of human and veterinary orthopedics addressing innovation and R&D facilities to combine multidrug nanovectors/nanotheranostic devices with tissue engineering. The translation of innovative nanodevices carried out on integrated pre-clinical and vet/human clinical settings will produce solid evidence-based datasets able to reduce fragmentation still limiting the impact of biomedical discoveries and to offer a unique opportunity for identifying new predictive biomarkers through the use of AI and deep learning data analysis.
Working across disciplines and sectors, P4 FIT will foster ESRs to be creative, critical, autonomous intellectual risk takers at the frontiers of research with the R&I mind-set necessary for thriving careers. P4 FIT will allow to fill the EU gap in tendon healthcare, building up a generation of researchers able to develop nano-based biomedical devices by integrating biology advances to technology innovation, and to computational revolution.
BUILD MULTIDISCIPLINARY EARLY STAGE RESEARCH EXPERTISE FOR FOSTERING FUTURE P4 MEDICAL SOLUTIONS APPLIED TO TENDON REPAIR AND DIAGNOSIS
P4 FIT is structured to generate a highly qualified research educational path and training cross-disciplinary platform, according to Leroy Hood in which “biology drives technology that drives computation”, to perceive P4 medical solutions in tendinopathy. More in detail, biological breakthroughs on tendon regenerative mechanisms will represent the advanced knowledge substrate driving technological innovations to apply to human and veterinary tendon diagnosis and therapy. The information and data generated inside P4 FIT and available in beneficiary and partner institutions will interpreted by taking advantage of computational tools to develop AI integrated approaches solving the individual clinical problems related to tendinopathy. Technological and computing outcomes, in turn, will open new biological frontiers, thus giving a more in depth knowledge of this poorly explored pathological tissue context.
INTER-DISCIPLINARY FOCUS AND INTERACTIONS AMONG THE 15 INDIVIDUAL ESRs
P4 FIT MANAGEMENT AND GOVERNING STRUCTURES